Lei Zhang1 Yuqin Zhang2 Yongmin Liu1

1, Northeastern University, Boston, Massachusetts, United States
2, Kunming University of Science and Technology, Kunming, , China

Extensive studies have indicated that integrating Ti metal of good mechanical properties with hydroxapatite (HA) ceramic of outstanding bioactivity and cytocompatibility can produce a suitable composite for biomedical implants. However, the addition of HA ceramic would deteriorate the mechanical obdurability and corrosion resistance of Ti alloy. In the present work, Ti-15.63 wt. % Ag alloy embedded with HA nanoparticles was synthesized by a combined route of spark plasma sintering (SPS) and mechanical alloying (MA). CaTiO3, Ca3(PO4)2 and TixPy generated during a eutectoid transformation of β-Ti→α-Ti+Ti2Ag. The dislocation movement of these ceramic phases regarding Ti2Ag as a carrier boosts the mechanicalobdurability of the composites. The in vitro test demonstrated that the Ti-15.63Ag-HA composites exhibit favorablemechanical obdurability, together with superior antibacterial properties (S. aureus) and cytocompatibility (MC3T3-E1). This work provides a strategy to design multifunctional Ti composites with enhanced mechanical properties and bioactivity and, specifically, the Ti-Ag-HA composite is expected to be apromising bone-implant biomaterial.