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Adnan Memic1 Tuerdimaimaiti Abudula1 Lassaad Gzara1 Giovanna Simonetti4 Ahmed AlShahrie1 Numan Salah1 Pierfrancesco Morganti5 Angelo Chianese4 Afsoon Fallahi2 Ali Tamayol3 Sidi Bencherif2

1, King Abdulaziz University, Jeddah, , Saudi Arabia
4, University of Rome, Sapienza, Rome, , Italy
5, Nanoscience Centre, MAVI Sud, Aprilia, , Italy
2, Northeastern University, Boston, Massachusetts, United States
3, University of Nebraska–Lincoln, Lincoln, Nebraska, United States

In the local treatment of both chronic and acute wounds it is crucial to prevent infections, control the removal of exudates and create a moist environment to allow for skin healing. To address these challenges it is necessary to develop the next generation of wound dressings. Chitin and lignin are bio-waste resulting from byproducts of crustacean crusts and plant biomass that have recently been proposed for bioengineering applications. However, their weak mechanical properties need. To accomplish this we fabricated hybrid mats composed of a chitin–lignin (CL)-based sol–gel mixture and elastomeric poly (glycerol sebacate) (PGS) using a standard electrospinning approach. Obtained results showed that PGS could be coherently blended with the sol–gel mixture to form a nanofibrous scaffold exhibiting remarkable mechanical performance and improved antibacterial and antifungal activity. The developed hybrid fibers showed promising potential in advanced biomedical applications such as wound care products. Ultimately, recycling these sustainable biopolymers and other bio-wastes alike could propel a “greener” economy.

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