Ahmed Busnaina1 2

1, Northeastern University, Boston, Massachusetts, United States
2, Nano OPS, Inc., Newton, Massachusetts, United States

Invention at the nanoscale promises to revolutionize novel bio-sensors that can detect a variety of biomarkers and chemicals chemical in the human body as well as pathogen detection. The NSF Nanoscale Science and Engineering Center for High-rate Nanomanufacturing has developed an entirely new disruptive nanoscale printing technology that will enable the printing of nanoscale sensors and electronics at a cost of 10-100 times less than conventional fabrication while allowing device designers to use of any organic or inorganic semiconducting, conductive or insulating material on flexible or rigid substrates. This will also include leveraging nanomaterials such as two-dimensional (2D) materials, quantum dots, etc. The new technology is enabled by directed assembly-based nanoscale printing at ambient temperature and pressure that prints 1000 times faster and 1000 smaller (down to 20nm) structures than ink-jet based printing. The technology enables a nanoscale printing platform, enabling heterogeneous integration of interconnected circuit layers (like CMOS) of printed electronics and sensors at ambient temperature and pressure.
The technology is used to print a novel biosensor and chemical sensor platform for real-time pathogen monitoring and for wearable sensors to monitor physiologic state or other chemicals and biomarkers in the body. These printed flexible sensors were also printed for wearable sensors that could be used as an electronic skin or for physiological monitoring as well as environmental monitoring. These wearable sensor that could detect glucose, urea and lactate levels using sweat. These inexpensive micro sensor with a low detection limit are typically less than 1 mm in size.